International Journal of Clinical Medicine
Vol.5 No.13(2014), Paper ID 47864, 12
pages
DOI:10.4236/ijcm.2014.513105
Bias-Variation Dilemma Challenges Clinical Trials: Inherent Limitations of Randomized Controlled Trials and Meta-Analyses Comparing Hernia Therapies
U. Klinge, Andreas Koch, D. Weyhe, Enrico Nicolo, R. Bendavid, Anette Fiebeler
Department of General, Visceral and Transplant Surgery, University Hospital of the RWTH, Aachen, Germany
Cottbus, Germany
Department of General and Visceral Surgery, Pius-Hospital Oldenburg, Oldenburg, Germany
Department of Surgery, University of Pittsburgh Medical Center, McKeesport, USA
Shouldice Hospital, Thornhill, Ontario, Canada
Berlin, Germany
Copyright © 2014 U. Klinge, Andreas Koch, D. Weyhe, Enrico Nicolo, R. Bendavid, Anette Fiebeler et al. This is
an open access article distributed under the Creative Commons Attribution
License, which permits unrestricted use, distribution, and reproduction in any
medium, provided the original work is properly cited.
How to Cite this Article
Klinge, U. , Koch, A. , Weyhe, D. , Nicolo, E. , Bendavid, R. and Fiebeler, A. (2014) Bias-Variation Dilemma Challenges Clinical Trials: Inherent Limitations of Randomized Controlled Trials and Meta-Analyses Comparing Hernia Therapies.
International Journal of Clinical Medicine,
5, 778-789. doi:
10.4236/ijcm.2014.513105.