Journal of Cancer Therapy

Vol.4 No.11A(2013), Paper ID 40800, 9 pages

DOI:10.4236/jct.2013.411A006

 

The PARP-1 Inhibitor Olaparib Causes Retention of γ-H2AX Foci in BRCA1 Heterozygote Cells Following Exposure to Gamma Radiation

 

Emma C. Bourton, Piers N. Plowman, Amanda J. Harvey, Sheba Adam Zahir, Christopher N. Parris

 

Brunel Institute of Cancer Genetics and Pharmacogenomics, Division of Biosciences, School of Health Sciences and Social Care, Brunel University, Uxbridge, UK
Department of Radiotherapy, St Bartholomew’s Hospital, West Smithfield, London, UK
Brunel Institute of Cancer Genetics and Pharmacogenomics, Division of Biosciences, School of Health Sciences and Social Care, Brunel University, Uxbridge, UK
Brunel Institute of Cancer Genetics and Pharmacogenomics, Division of Biosciences, School of Health Sciences and Social Care, Brunel University, Uxbridge, UK
Brunel Institute of Cancer Genetics and Pharmacogenomics, Division of Biosciences, School of Health Sciences and Social Care, Brunel University, Uxbridge, UK

 

Copyright © 2013 Emma C. Bourton, Piers N. Plowman, Amanda J. Harvey, Sheba Adam Zahir, Christopher N. Parris et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

 

How to Cite this Article


E. Bourton, P. Plowman, A. Harvey, S. Zahir and C. Parris, "The PARP-1 Inhibitor Olaparib Causes Retention of γ-H2AX Foci in BRCA1 Heterozygote Cells Following Exposure to Gamma Radiation," Journal of Cancer Therapy, Vol. 4 No. 11A, 2013, pp. 44-52. doi: 10.4236/jct.2013.411A006.

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