Food and Nutrition Sciences
Vol.3 No.4(2012), Paper ID 18504, 8
pages
DOI:10.4236/fns.2012.34077
Isoleucine, an Essential Amino Acid, Induces the Expression of Human β Defensin 2 through the Activation of the G-Protein Coupled Receptor-ERK Pathway in the Intestinal Epithelia
Youkou Konno, Toshifumi Ashida, Yuhei Inaba, Takahiro Ito, Hiroki Tanabe, Atsuo Maemoto, Tokiyoshi Ayabe, Yusuke Mizukami, Mikihiro Fujiya, Yutaka Kohgo
Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa, Japan
IBD Center, Sapporo Higashi Tokushukai Hospital, Sapporo, Japan
Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa, Japan
Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa, Japan
Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa, Japan
IBD Center, Sapporo Higashi Tokushukai Hospital, Sapporo, Japan
Innate Immunity Laboratory, Department of Cellular Life Science, Faculty of Advanced Life Science, Hokkaido University, Sapporo, Japan
Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa, Japan
Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa, Japan
Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa, Japan
Copyright © 2012 Youkou Konno, Toshifumi Ashida, Yuhei Inaba, Takahiro Ito, Hiroki Tanabe, Atsuo Maemoto, Tokiyoshi Ayabe, Yusuke Mizukami, Mikihiro Fujiya, Yutaka Kohgo et al. This is
an open access article distributed under the Creative Commons Attribution
License, which permits unrestricted use, distribution, and reproduction in any
medium, provided the original work is properly cited.
How to Cite this Article
Y. Konno, T. Ashida, Y. Inaba, T. Ito, H. Tanabe, A. Maemoto, T. Ayabe, Y. Mizukami, M. Fujiya and Y. Kohgo, "Isoleucine, an Essential Amino Acid, Induces the Expression of Human
β Defensin 2 through the Activation of the G-Protein Coupled Receptor-ERK Pathway in the Intestinal Epithelia,"
Food and Nutrition Sciences, Vol. 3 No. 4, 2012, pp. 548-555. doi:
10.4236/fns.2012.34077.