Open Journal of Respiratory Diseases

Vol.2 No.1(2012), Paper ID 17694, 8 pages

DOI:10.4236/ojrd.2012.21001

 

Effects of Clarithromycin at Sub-Minimum Inhibitory Concentrations on Early ermB Gene Expression, Metabolic Activity and Growth of an erm(B)-Expressing Macrolide-Resistant Strain of Streptococcus pneumoniae

 

Riana Cockeran, H. C. Steel, N. Wolter, L. de Gouveia, A. von Gottberg, K. P. Klugman, A. T. Leanord, D. J. Inverarity, T. J. Mitchell, C. Feldman, R. Anderson

 

Medical Research Council (MRC) Unit for Inflammation and Immunity, Department of Immunology, Faculty of Health Sciences, University of Pretoria, and Tshwane Academic Division of the National Health Laboratory Service, Pretoria, South Africa
Medical Research Council (MRC) Unit for Inflammation and Immunity, Department of Immunology, Faculty of Health Sciences, University of Pretoria, and Tshwane Academic Division of the National Health Laboratory Service, Pretoria, South Africa
Respiratory and Meningeal Pathogens Research Unit, National Institute for Communicable Diseases of the National Health Laboratory Service and Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Respiratory and Meningeal Pathogens Research Unit, National Institute for Communicable Diseases of the National Health Laboratory Service and Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Respiratory and Meningeal Pathogens Research Unit, National Institute for Communicable Diseases of the National Health Laboratory Service and Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Hubert Department of Global Health, Rollins School of Public Health, and Division of Infectious Diseases, School of Medicine, Emory University, Atlanta, USA
Microbiology Department, Southern General Hospital, Glasgow, UK
Division of Infection and Immunity, Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, UK
Division of Infection and Immunity, Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, UK
Division of Pulmonology, Department of Internal Medicine, Charlotte Maxeke Johannesburg Academic Hospital and University of the Witwatersrand, Johannesburg, South Africa
Medical Research Council (MRC) Unit for Inflammation and Immunity, Department of Immunology, Faculty of Health Sciences, University of Pretoria, and Tshwane Academic Division of the National Health Laboratory Service, Pretoria, South Africa

 

Copyright © 2012 Riana Cockeran, H. C. Steel, N. Wolter, L. de Gouveia, A. von Gottberg, K. P. Klugman, A. T. Leanord, D. J. Inverarity, T. J. Mitchell, C. Feldman, R. Anderson et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

 

How to Cite this Article


R. Cockeran, H. Steel, N. Wolter, L. Gouveia, A. Gottberg, K. Klugman, A. Leanord, D. Inverarity, T. Mitchell, C. Feldman and R. Anderson, "Effects of Clarithromycin at Sub-Minimum Inhibitory Concentrations on Early ermB Gene Expression, Metabolic Activity and Growth of an erm(B)-Expressing Macrolide-Resistant Strain of Streptococcus pneumoniae," Open Journal of Respiratory Diseases, Vol. 2 No. 1, 2012, pp. 1-8. doi: 10.4236/ojrd.2012.21001.

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