Sickle cell disease (SCD) is a group of blood disorders typically inherited from a person's parents. The most common type is known as sickle cell anaemia (SCA). It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells. This leads to a rigid, sickle-like shape under certain circumstances.

In the present book, fifteen typical literatures about sickle cell disease published on international authoritative journals were selected to introduce the worldwide newest progress, which contains reviews or original researches on sickle cell crisis, acute chest syndrome, malaria prevention, vaso-occlusive crisis, avascular necrosis, etc. We hope this book can demonstrate advances in sickle cell disease as well as give references to the researchers, students and other related people.