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  • 239pp. Published July 2017
  • Scientific Research Publishing, Inc.,USA.
  • Category: Medicine & Healthcare
  • ISBN: 978-1-61896-391-8
  • (Paperback) USD 89.00
  • ISBN: 978-1-61896-392-5
  • (E-Book) USD 29.00

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Home > Books > Ultrastructure of the Human Testis from ...
Ultrastructure of the Human Testis from Birth to Senility
  • Description
  • E-Book
  • Author(s) Information

From birth to puberty the testis is a dynamic structure, and the knowledge of its evolution is an important consideration in interpreting biopsies from children. On the other hand, in the normal adult testis, it is frequent to find several peculiar structures which might be misinterpreted as anomalies when the pathologist does not have a good grasp of the subject. It is also to take into account that the testis shows progressive alterations with age. Most of them are not specific and should not be but are present in a variety of pathologies.


The present work is the results of several decades studying testicular biopsy and autopsy specimens by the authors, who have selected the most relevant material and ordered it to illustrate the evolution of the human testis from birth to senility. Micrographs were taken in the Service of Pathology of the La Paz Hospital, Madrid, and the University Clinic of Salamanca, Spain. These pictures offer many well-known facts and new findings which have not been published elsewhere.

Components of the Book:
  • FRONT MATTER
  • PART I: THE TESTIS FROM BIRTH TO PUBERTY
    • FIGURE 1. PREPUBERTAL TESTIS: NEWBORN TESTIS
    • FIGURE 2. PREPUBERTAL TESTIS: INFANTILE TESTIS
    • FIGURE 3. PREPUBERTAL TESTIS: Ap AND Ad SPERMATOGONIA
    • FIGURE 4. A SPERMATOGONIA: THE NUCLEOLI
    • FIGURE 5. A SPERMATOGONIA: NUCLEAR ENVELOPE AND INTERMITOCHONDRIAL BARS
    • FIGURE 6. A SPERMATOGONIA: THE NUAGE AND THE LUBARSCH'S CRYSTALS
    • FIGURE 7. A SPERMATOGONIA: INTRANUCLEAR BODIES AND INTERCELLULAR BRIDGES
    • FIGURE 8. A SPERMATOGONIA: VACUOLES AND CILIA. B SPERMATOGONIA
    • FIGURE 9. PRIMARY SPERMATOCYTES IN INFANT TESTES
    • FIGURE 10. THE PREPUBERTAL SERTOLI CELL
    • FIGURE 11. THE PREPUBERTAL SERTOLI CELL FILAMENTS
    • FIGURE 12. THE TUNICA PROPRIA AND TESTICULAR INTERSTITIUM OF THE PREPUBERTAL TESTIS
    • FIGURE 13. THE TUNICA PROPRIA OF THE PREPUBERTAL TESTIS
    • FIGURE 14. LEYDIG CELLS IN THE PREPUBERTAL TESTIS
    • FIGURE 15. PERITUBULAR LEYDIG CELLS IN THE PREPUBERTAL TESTIS
    • FIGURE 16. PUBERTAL TESTIS. THE ONSET OF SERTOLI CELL MATURATION
    • FIGURE 17. PUBERTAL TESTIS. MATURATION OF THE SERTOLI CELL AND THE BASAL LAMINA
    • FIGURE 18. PUBERTAL TESTIS. LEYDIG CELL DIFFERENTIATION
  • PART II: THE ADULT TESTIS
    • FIGURE 19. SEMINIFEROUS TUBULES
    • FIGURE 20. SCANNING ELECTRON MICROSCOPY
    • FIGURE 21. TYPES OF SPERMATOGONIA
    • FIGURE 22. Ad, Ap AND Ac SPERMATOGONIA
    • FIGURE 23. AL SPERMATOGONIA
    • FIGURE 24. A SPERMATOGONIA: NUCLEOLI AND INTRANUCLEAR BODIES
    • FIGURE 25. A SPERMATOGONIA: BLEBS AND STRIPES OF THE NUCLEAR ENVELOPE, AND MITOCONDRIA
    • FIGURE 26. B SPERMATOGONIA
    • FIGURE 27. MITOSES IN SPERMAGONIA
    • FIGURE 28. PRIMARY SPERMATOCYTES: INTERPHASE, LEPTOTENE AND ZYGOTENE STAGES
    • FIGURE 29. PRIMARY SPERMATOCYTES: SYNAPTONEMAL COMPLEXES
    • FIGURE 30. PRIMARY SPERMATOCYTES: PACHYTENE
    • FIGURE 31. LAST STAGES OF THE FIRST MEIOTIC DIVISION
    • FIGURE 32. SECONDARY SPERMATOCYTES
    • FIGURE 33. SPERMATIDS: START OF THE ACROSOME AND FLAGELLUM
    • FIGURE 34. SPERMATIDS: ANNULATE LAMELLAE AND CHROMATOID BODY
    • FIGURE 35. SPERMATIDS: ACROSOME DEVELOPMENT AND START OF NUCLEAR ELONGATION
    • FIGURE 36. SPERMATIDS: FLAGELLUM DEVELOPMENT AND PECULIAR STRUCTURES
    • FIGURE 37. SPERMATIDS: THE ACROSOME STRUCTURE AND NUCLEOLAR REGRESSION
    • FIGURE 38. SPERMATIDS: THE FUSIFORM BODY, THE MANCHETTE AND CHROMATIN CONDENSATION
    • FIGURE 39. SPERMATIDS: THE FLAGELLUM NECK
    • FIGURE 40. SPERMATOGENESIS. GERM CELL LINE DEVELOPMENT
    • FIGURE 41. SPERMATOZOOA
    • FIGURE 42. THE SPERMATOZOON STRUCTURE
    • FIGURE 43. THE CYCLE OF THE SEMINIFEROUS EPITHELIUM: STAGES OF THE CYCLE
    • FIGURE 44. THE CYCLE OF THE SEMINIFEROUS EPITHELIUM: SIGNIFICANCE OF THE CYCLE
    • FIGURE 45. THE SERTOLI CELL
    • FIGURE 46. SERTOLI CELLS: THE NUCLEUS
    • FIGURE 47. SERTOLI CELLS: THE CYTOPLASM
    • FIGURE 48. SERTOLI CELLS: ANNULATE LAMELLAE
    • FIGURE 49. INTER SERTOLI CELL JUNCTIONAL SPECIALIZATIONS
    • FIGURE 50. SERTOLI CELL-GERM CELL JUNCTIONS AND INNERVATION
    • FIGURE 51. THE TUNICA PROPRIA: THE BASEMENT MEMBRANE
    • FIGURE 52. THE TUNICA PROPRIA: THE PERITUBULAR CELLS
    • FIGURE 53. THE LEYDIG CELL
    • FIGURE 54. LEYDIG CELLS: REINKE’S CRYSTALS
    • FIGURE 55. LEYDIG CELLS: LIPIDS, LYSOSOMES AND CILIA
    • FIGURE 56. LEYDIG CELLS: JUNCTIONS, INNERVATION AND MITOSES
    • FIGURE 57. OTHER CELLS OF THE TESTICULAR INTERSTITIUM
  • PART III: THE AGING TESTIS
    • FIGURE 58. TESTICULAR INVOLUTION WITH AGING
    • FIGURE 59. STAGES OF SEMINIFEROUS TUBULES INVOLUTION
    • FIGURE 60. GERM CELL DEATH AND SLOUGHING
    • FIGURE 61. SPERMATOGONIAL ANOMALIES
    • FIGURE 62. SPERMATOCYTE ANOMALIES
    • FIGURE 63. DISLOCATED AND MULTINUCLEATE SPERMATIDS
    • FIGURE 64. SPERMATIDS WITH ACROSOMAL MALFORMATIONS
    • FIGURE 65. SPERMATIDS WITH NUCLEAR AND CYTOPLASMIC MALFORMATIONS
    • FIGURE 66. SPERMATOZOON MALFORMATIONS
    • FIGURE 67. COLIED TAILS AND BIFLAGELLATE SPERMATOZOA
    • FIGURE 68. SERTOLI CELLS ANOMALIES: LIPIDS AND VACUOLES
    • FIGURE 69. SERTOLI CELLS ANOMALIES: EXTENSIVE JUNCTIONAL SPECIALIZATIONS AND MULTINUCLEATION
    • FIGURE 70. SERTOLI CELL ANOMALIES: MITOCHONDRIAL METAPLASIA AND DEDIFFERENTIATION
    • FIGURE 71. SERTOLI CELL ANOMALIES: KERATIN EXPRESSION AND DECREASE IN VIMENTIN
    • FIGURE 72. TUNICA PROPRIA ANOMALIES: COLLAGENIZATION AND BASAL LAMINA ALTERATIONS
    • FIGURE 73. TUNICA PROPRIA ANOMALIES: DECREASED ACTIN AND DESMIN EXPRESSION
    • FIGURE 74. LEYDIG CELL ALTERATIONS: MULTINUCLEATION AND INCREASED LIPOFUSCIN CONTENT
    • FIGURE 75. LEYDIG CELL ALTERATIONS: MULTIVACUOLATED, LIPID-LOADED CELLS
    • FIGURE 76. LEYDIG CELL ALTERATIONS: INCREASED REINKE’S CRYSTALS AND PARACRYSTALLINE INCLUSIONS
    • FIGURE 77. LEYDIG CELL ALTERATIONS: INTRANUCLEAR INCLUSIONS AND DEDIFFERENTIATION
    • FIGURE 78. LEYDIG CELL ALTERATIONS: DIMINISHED TESTOSTERONE SYNTHESIS
  • PART IV: REFERENCES
Readership: Medicine professionals and /or researchers involved in the above mentioned fields.
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