The microRNA 2000: from HIV-1 to Healthcare

microRNA (miRNA), like a language, is full of regulators for our lives. Function of miRNAs is simple to tell – for instance, post-transcriptional suppression; however, its mechanisms are more tricky and explanation of miRNAs’ role in evolution causes difficulty even graduated students and top researchers. How exactly is the information of miRNA used? What is the difference between CeRNA theory and RNA wave 2000? What are the real rules for disease induction and cure? When do we use the expression of miRNAs? How do you say, miRNA is information and not epigene? Where does miRNA locate? When are miRNAs transmitted? And so on, and so on.

 

This book would be a practical reference guide to problems of these kinds. But there is no point that is lie or truth. Therefore, the book is intend for not only intermediate and advanced scientists or students but also scientific enthusiasts. Being references, it contains information at various journals, ranging from review articles to very unique articles. Finally readers would decide lie or truth, or near pin or not because research of concept in miRNAs is in progress day by day by over 10,000 references per year on 2016.



Components of the Book:
  • FRONT MATTER
  • Chapter 1: Gardener of miRNA in Oxford
    • Overview
    • 1.1. 1987 Oxford
    • 1.2. 1983 Mobile RNA Element
    • 1.3. 1998 Fire and Mellow
    • 1.4. Built up STYLE
    • 1.5. Sniper of miRNA for HIV-1
    • 1.6. At 2000 RNA Wave
    • 1.7. At 2012 Food in miRNA
    • References
  • Chapter 2: Mobile miRNAs: Possible Biogenesis of the microRNAs
    • Overview
    • 2.1. Tribute of RNA Wave 2000
    • 2.2. New Biogenesis Map of miRNAs
    • 2.3. Big Pool of Circulating miRNA vs. Small Pool of miRNA with microRNA-Induced Silencing Complex (miRISC)
    • 2.4. Circulating Torus miRNA
    • 2.5. miRNA-miRNA Programming
    • 2.6. Seed Theory Programming
    • 2.7. G Synergism
    • References
  • Chapter 3: Food xenomiRNA Arise: The microRNA Storm and Universe
    • Overview
    • 3.1. miRNA Storm
    • 3.2. xenomiRNAs in Microvesicles of Foods
    • 3.3. The xenomiRNA as Magic Ballet
    • 3.4. The miRNA Genotype
    • 3.5. SIRT1 Connection
    • 3.6. Neurodegenerative Obesity
    • 3.7. Cardiometabolic Information Nexus
    • 3.8. MiR-33 Pivot
    • 3.9. NF-κB upon Inflammation
    • 3.10. A New Food Information Processing
    • References
  • Chapter 4: microRNA as Brain Memory Device in the Microvesicles
    • Overview
    • 4.1. miRNA Memory
    • 4.2. Role of miRNA in Synapse
    • 4.3. Memory Type and its Location
    • 4.4. Synaptic Plasticity with miRNAs
    • 4.5. Neuroplasticity by Secreting Synaptosome miRNAs
    • 4.6. Mobile Retroelements for Plasticity
    • 4.7. Food miRNA Intake with Prion
    • References
  • Chapter 5: Progammed Evolution by miRNA Memory Package
    • Overview
    • 5.1. Programmed Evolution
    • 5.2. An Acquired Phenotype
    • 5.3. Quantum Theory of RNA Waves
    • 5.4. Quantum Turing miRNA Information
    • 5.5. MiR-AI
    • References
  • Chapter 6: Commune in Inflammation and Cancer miRNAs
    • Overview
    • 6.1. Non-Coding Proto-Oncogene
    • 6.2. Burkitt’s Lymphoma Information by miR-155
    • 6.3. Anti-Infla/Oncomir miR-34
    • 6.4. miR-21 and NOS
    • 6.5. miR-17-92 Family Linking to the miRNA Surveillance
    • 6.6. Unknown Mdm2 Control
    • References
  • Chapter 7: The Concept of “Virus” Is the Same as that of the miRNA Gene in the Eosomes
    • Overview
    • 7.1. Colander for miRNAs
    • 7.2. Gammaherpesvirus
    • 7.3. HIV-1
    • 7.4. Influenza Virus
    • 7.5. Tropic Viruses
    • References
  • Chapter 8: ES Cell or iPS Cell, Yes or No, That Is Question
    • Overview
    • 8.1. Stem Cell Love Letter in the Bottle
    • 8.2. The miRNA Direct Reprogramming
    • 8.3. GVHD in Stem Cells
    • 8.4. Escape from High Wall
    • References
  • Chapter 9: “MIRAI” Medical Care: “Future” in Japanese
    • Overview
    • 9.1. RNA Quantum Language for Clinic
    • 9.2. Sample Source of Circulating miRNA
    • 9.3. Chaos and Fuzzy: Diagnosis to Therapy Information Flow
    • 9.4. Universal MMP of miRNAs in Human Disease
    • 9.5. miR-34 Surveillance
    • 9.6. MIRAI System for Healthcare
    • References
  • Chapter 10: Deep Learning of miRNA for Therapeutic Application
    • Overview
    • 10.1. Edible miRNA Controls Mendelian and Darwinism
    • 10.2. The Next Stage of Specific Delivery
    • 10.3. N367 Orthologue
    • 10.4. HIV Edible Vaccine
    • References
  • BACK MATTER
    • References
    • Index
Readership: University students, Graduated students, Scientific enthusiasts who are interesting in Biology, Medicine, Pharmaceutical Science, Informational Technology, Computing, Agriculture, Nutrition.
1
FRONT MATTER
PDF (8266 KB)
11
Chapter 1: Gardener of miRNA in Oxford
PDF (2374 KB)
31
Chapter 2: Mobile miRNAs: Possible Biogenesis of the microRNAs
PDF (17469 KB)
62
Chapter 3: Food xenomiRNA Arise: The microRNA Storm and Universe
PDF (21436 KB)
110
Chapter 4: microRNA as Brain Memory Device in the Microvesicles
PDF (10262 KB)
136
Chapter 5: Progammed Evolution by miRNA Memory Package
PDF (25851 KB)
160
Chapter 6: Commune in Inflammation and Cancer miRNAs
PDF (14597 KB)
192
Chapter 7: The Concept of “Virus” Is the Same as that of the miRNA Gene in the Eosomes
PDF (16246 KB)
214
Chapter 8: ES Cell or iPS Cell, Yes or No, That Is Question
PDF (14177 KB)
232
Chapter 9: “MIRAI” Medical Care: “Future” in Japanese
PDF (1004 KB)
257
Chapter 10: Deep Learning of miRNA for Therapeutic Application
PDF (16767 KB)
269
BACK MATTER
PDF (5541 KB)
Dr. Yoichi Robertus Fujii (Biography), Society of microRNA in Japan, Memebership: NY Acad. Sci. (-2006), Japanese Association of Virology (-2015), Japanese Association of Veterinary Medicine (-2015), Society of microRNA in Japan (2015-)

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