Type 1 diabetes (also known as Diabetes mellitus type 1) is a form of diabetes mellitus in which not enough insulin is produced. The lack of insulin results in high blood sugar levels. The classical symptoms of type 1 diabetes are frequent urination, increased thirst, increased hunger, and weight loss. Additional symptoms may include blurry vision, feeling tired and poor healing. The cause of type 1 diabetes is unknown. It however is believed to involve a combination of genetic and environmental factors. Risk factors include having a family member with the condition. The underlying mechanism involves an autoimmune destruction of the insulin-producing beta cells in the pancreas. Diabetes is diagnosed by testing the level of sugar or A1C in the blood. Type 1 diabetes may be distinguished from type 2 by autoantibody testing.

In the present book, twelve typical literatures about type 1 diabetes published on international authoritative journals were selected to introduce the worldwide newest progress, which contains reviews or original researches on medical science, autoimmune diseases, enterovirus-associated diseases, epidemiology, ect. We hope this book can demonstrate advances in type 1 diabetes as well as give references to the researchers, students and other related people.