Advances in Hepatitis B Treatment

Hepatitis B is an infectious disease caused by the hepatitis B virus (HBV) which affects the liver. The virus is transmitted by exposure to infectious blood or body fluids. Infection around the time of birth or from contact with other people’s blood during childhood is the most frequent method by which hepatitis B is acquired in areas where the disease is common. Acute hepatitis B infection does not usually require treatment and most adults clear the infection spontaneously. Early antiviral treatment may be required in fewer than 1% of people, whose infection takes a very aggressive course (fulminant hepatitis) or who are immune-compromised. On the other hand, treatment of chronic infection may be necessary to reduce the risk of cirrhosis and liver cancer. Treatment lasts from six months to a year, depending on medication and genotype. Although none of the available drugs can clear the infection, they can stop the virus from replicating, thus minimizing liver damage.


In the present book, fifteen typical literatures about Hepatitis B treatment published on international authoritative journals were selected to introduce the worldwide newest progress, which contains reviews or original researches on medical science, virus disease, virology, epidemiology, ect. We hope this book can demonstrate advances in Hepatitis B treatment as well as give references to the researchers, students and other related people.

Components of the Book:
  • Chapter 1
    Asian-Pacific Clinical Practice Guidelines on the Management of Hepatitis B: A 2015 Update
  • Chapter 2
    Cost‑Effectiveness Analysis of Oral Anti‑Viral Drugs Used for Treatment of Chronic Hepatitis B in TurkeyCost‑Effectiveness Analysis of Oral Anti‑Viral Drugs Used for Treatment of Chronic Hepatitis B in Turkey
  • Chapter 3
    Entecavir plus Adefovir Rescue Therapy for Chronic Hepatitis B Patients after Multiple Treatment Failures in Real-Life Practice
  • Chapter 4
    Efficacy and Resistance in De Novo Combination Lamivudine and Adefovir Dipivoxil Therapy versus Entecavir Monotherapy for the Treatment-Naive Patients with Chronic Hepatitis B: A Meta-Analysis
  • Chapter 5
    Meta-Analysis of the Short-Term Effects of Lamivudine Treatment for Severe Chronic Hepatitis B
  • Chapter 6
    Informing the Design of a National Screening and Treatment Programme for Chronic Viral Hepatitis in Primary Care: Qualitative Study of At-Risk Immigrant Communities and Healthcare Professionals
  • Chapter 7
    Proportion and Factors Associated with Hepatitis B Viremia in Antiretroviral Treatment Naïve and Experienced HIV Co-Infected Ghanaian Patients
  • Chapter 8
    Reactivation of Occult Hepatitis B Virus Infection under Treatment with Abatacept: A Case Report
  • Chapter 9
    HBsAg as an Important Predictor of HBeAg Seroconversion Following Antiviral Treatment for HBeAg-Positive Chronic Hepatitis B Patients
  • Chapter 10
    Short‑Term Treatment Outcomes in Human Immunodeficiency Virus Type‑1 and Hepatitis B Virus Co‑Infections
  • Chapter 11
    Telbivudine for the Treatment of Chronic Hepatitis B in HBeAg‑Positive Patients in China: A Health Economic Analysis
  • Chapter 12
    Tenofovir Rescue Therapy in Chronic Hepatitis B Patients Who Failed Previous Nucleoside Analogue Treatment
  • Chapter 13
    On-Treatment Mortality Predictors in Chronic Hepatitis B Patients Experiencing Severe Acute Exacerbation: A Prospective Observational Study
  • Chapter 14
    Off-Treatment Virologic Relapse and Outcomes of Re-Treatment in Chronic Hepatitis B Patients Who Achieved Complete Viral Suppression with Oral Nucleos(T)Ide Analogs
  • Chapter 15
    13-Year Nationwide Cohort Study of Chronic Kidney Disease Risk among Treatment-NaïVe Patients with Chronic Hepatitis B in Taiwan
Readership: Students, academics, teachers and other people attending or interested in Hepatitis B Treatment.
Lorna Sweeney, Institute for Health and Human Development, University of East London, UH250, Stratford Campus, Water Lane, London, UK

Timothy N. A. Archampong, Department of Medicine and Therapeutics, School of Medicine and Dentistry, College of Health Sciences, University of Ghana, Accra, Ghana

Rossella Talotta, Rheumatology Unit, University Hospital “Luigi Sacco”, Via GB Grassi 74, Milan, Italy

Lan-Juan Li, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China

Dorota Kozielewicz, Department of Infectious Diseases and Hepatology, Faculty of Medicine, Nicolaus Copernicus University in Toruń, ul. ?w. Floriana 12, 85 030 Bydgoszcz, Poland

Jin-Wook Kim, Department of Medicine, Seoul National University Bundang Hospital, 300 Gumi-dong, Bundang-gu, Seongnam-si, Gyeonggi-do 463-707, South Korea

and more...
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