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  • 481pp. Published January 2016
  • Scientific Research Publishing
  • Category: Medicine & Healthcare
  • ISBN: 978-1-61896-146-4
  • (Hardcover) USD 109.00
  • ISBN: 978-1-61896-145-7
  • (Paperback) USD 89.00
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Advances in Next-Generation Sequencing Approaches
  • Description
  • Author(s) Information
The high demand for low-cost sequencing has driven the development of high-throughput sequencing, which is also termed as Next generation sequencing (NGS). Thousands or millions of sequences concurrently produced in next-generation sequencing process. The current sources for NGS informatics are extremely fragmented. A novice could read review articles in this book, follow discussion threads on forums. Finding a centralized synthesis is much more difficult. Books are available, and the development of the field is so fast that book chapters risk being obsoleted. Moreover, thanks for a handful of authors to continually update their text which take up a lot of their schedule.
Components of the Book:
  • FRONT MATTER
  • Chapter 1
    Next-Generation Sequencing in Clinical Oncology: Next Steps Towards Clinical Validation
  • Chapter 2
    Next-generation sequencing reveals novel differentially regulated mRNAs, lncRNAs, miRNAs, sdRNAs and a piRNA in pancreatic cancer
  • Chapter 3
    Molecular Typing of Lung Adenocarcinoma on Cytological Samples Using a Multigene Next Generation Sequencing Panel
  • Chapter 4
    Next-generation sequencing for genetic testing of familial colorectal cancer syndromes
  • Chapter 5
    Targeted next generation sequencing of RB1 gene for the molecular diagnosis of Retinoblastoma
  • Chapter 6
    Next generation sequencing of triple negative breast cancer to find predictors for chemotherapy response
  • Chapter 7
    Circulating tumor cells in hepatocellular carcinoma: a pilot study of detection, enumeration, and next-generation sequencing in cases and controls
  • Chapter 8
    Retrospective review using targeted deep sequencing reveals mutational differences between gastroesophageal junction and gastric carcinomas
  • Chapter 9
    Tumor evolution and intratumor heterogeneity of an epithelial ovarian cancer investigated using next-generation sequencing
  • Chapter 10
    Mutation analysis of Chinese sporadic congenital sideroblastic anemia by targeted capture sequencing
  • Chapter 11
    Development and analytical validation of a 25-gene next generation sequencing panel that includes the BRCA1 and BRCA2 genes to assess hereditary cancer risk
  • Chapter 12
    Next-Generation Sequencing of RNA and DNA Isolated from Paired Fresh-Frozen and Formalin-Fixed Paraffin-Embedded Samples of Human Cancer and Normal Tissue
  • Chapter 13
    Analysis of Pre-Analytic Factors Affecting the Success of Clinical Next-Generation Sequencing of Solid Organ Malignancies
  • Chapter 14
    Genome sequencing and next-generation sequence data analysis: A comprehensive compilation of bioinformatics tools and databases
  • Chapter 15
    Whole-genome sequencing to control antimicrobial resistance
  • Chapter 16
    Phase-defined complete sequencing of the HLA genes by next-generation sequencing
  • Chapter 17
    A high-throughput screening strategy for detecting CRISPR-Cas9 induced mutations using next-generation sequencing
  • Chapter 18
    Cancer research in the era of next-generation sequencing and big data calls for intelligent modeling
  • Chapter 19
    Next-generation sequencing: hype and hope for development of personalized radiation therapy?
Readership: Clinical practitioners and scientists; professionals in cancer therapy and DNA sequencing; medicaland biological students.
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