An Innovative Concept Gel to Prevent Skin Aging

Adele Sparavigna, Beatrice Tenconi, Ileana Deponti, Francesco Scarci, Maurizio Caserini, Federico Mailland

Derming, Clinical Research and Bioengineering Institute, Monza, Italy.
Scientific Department, Polichem S. A., Lugano, Switzer-land.

DOI: 10.4236/jcdsa.2013.34041                

Abstract

The study aimed to evaluate the instrumental and clinical properties of an innovative gel formulation for anti-aging treatment. This was an open, non-controlled study, where the eligible subjects, divided into three subgroups according to age, had to perform a single dose application of the gel on the face for a short-term evaluation and a 4-week repeated use, twice a day, for a long-term evaluation. Instrumental and clinical evaluations had to be performed mono-laterally at the level of the face (right or left side according to a predisposed randomization list) in basal conditions (T₀), 20 minutes after the first dose application (T_20min) and after 2 and 4 weeks of treatment (T_2wks - T_4wks). Thirty-three subjects completed the study showing, after only 20 minutes from the 1^st product application, a clinically important and statistically significant improvement of crow’s feet, skin dullness clinical score and cutaneous microrelief clinical score (p < 0.05), after 2 weeks of treatment an improvement of skin tonicity (p < 0.05) and after 4 weeks of treatment having a significant decrease of nasolabial folds clinical score (p < 0.05). The study showed the great efficacy of an innovative anti-aging gel in reducing the skin roughness and skin dryness, improving the skin firmness and, in general, providing a global skin rejuvenation.

Keywords

Skin; Wrinkles; Anti-Aging

Conflicts of Interest

The authors declare no conflicts of interest.

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