Koenderink, J.B., Van Den Heuvel, J.J.M.W., Bilos, A., Vredenburg, G., Vermeulen, N.P.E. and Russel, F.G.M. (2020) Human Multidrug Resistance Protein 4 (MRP4) Is a Cellular Efflux Transporter for Paracetamol Glutathione and Cysteine Conjugates. Archives of Toxicology, 94, 3027-3032.
https://doi.org/10.1007/s00204-020-02793-4

has been cited by the following article:

• TITLE: The Protective Effect of Moringa oleifera Leaves Extract on Paracetamol Hepatotoxicity in Male Rats

  AUTHORS: Reham M. Al-Sultan, Noorah Saleh Al-Sowayan

  KEYWORDS: Moringa oleifera, Paracetamol, Hepatotoxicity, Oxidative Stress

  JOURNAL NAME: Journal of Biomedical Science and Engineering, Vol.17 No.3, March 20, 2024

  ABSTRACT: In recent years, there has been an increase in concern regarding the effects of paracetamol poisoning on liver tissues, particularly when consumed in large amounts. Some studies have estimated that paracetamol is involved in 56% of acute liver diseases, whereas 0.4% of paracetamol overdose cases result in fatal-ity. In this study, the effects of Moringa oleifera on paracetamol toxicity in the liver were explored. It has been demonstrated that Moringa oleifera is highly nu-tritious, contains bioactive molecules, and is therapeutically beneficial. Many studies have shown that Moringa oleifera leaves possess a wide range of biologi-cal properties, including antioxidant, tissue protection, analgesic, antihyperten-sive, and immunomodulatory activities. This study highlights the protective role of Moringa oleifera on handling possible paracetamol hepatotoxicity in male rats.