TITLE:
Isolated Autoimmune Orchitis Due to IgG4 Hypersecretion Presenting as Tumor-Like Mass: Case Report and Review of Literature
AUTHORS:
Francisco Marcos da Silva Barroso, Flavio Antunes de Sousa, Paloma Menezes de Souza, Gustavo Lopes de Castro, Katia Ramos Moreira Leite, Monique Freire Santana, Roger Arthur da Cunha Alves, Gabriela Ayumi Owada Borges, Juan Eduardo Rios Rodriguez
KEYWORDS:
Orchitis, IgG4-Related Disease, Autoimmune, Testicle, Inflammatory
JOURNAL NAME:
Open Journal of Urology,
Vol.12 No.1,
January
17,
2022
ABSTRACT: Background: IgG4-related disease is a rare autoimmune condition that presents with lymphoplasmacytic infiltrate and fibrosis in the organ affected. Isolated testicle involvement is uncommon and there are only a few cases reported in the literature. Case Presentation: We report a case of isolated chronic orchitis due to IgG4 hypersecretion in a 61-year-old patient that evolved with asymptomatic tumor-like mass growth and was treated with left orchiectomy. Histopathological study revealed orchitis related to IgG4 hypersecretion disease. Conclusion: IgG4-related disease can be manifested as a multi or single-organ disorder. Most diagnoses are made after surgery with histopathological analysis. Most of the cases in literature stand out the difficulty in diagnosis and necessity of high suspicion due to this condition’s similarity with neoplasm presentation.