TITLE:
Demographic and Assisted Reproduction Related Factors Associated with Dichorionic Triplet Gestations
AUTHORS:
Barbara V. Parilla, Brett Goldman, Sue Jasulaitis, Suela Sulo, Angeline Beltsos
KEYWORDS:
Monochorionic, Triplets, Embryo Splitting
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.5 No.13,
November
10,
2015
ABSTRACT: Our objective was to evaluate which demographic factors or assisted
reproductive technologies were associated with IVF triplet gestations where one
of the embryos split, resulting in a dichorionic triplet gestation. This was a
case-control study of dichorionic versus trichorionic triplet gestations that
underwent assisted reproductive technology over the last 5 years at our fertility
center. There were 53 cases of dichorionic triamniotic triplet gestations
compared to 119 trichorionic triplet controls. There were no significant
demographic differences between the cases and controls. 51/53 dichorionic
triplets and 86/119 trichorionic triplets were conceived through IVF, the
remaining utilized intrauterine insemination. ICSI was performed in virtually
all patients that underwent IVF. Of the potential risk factors studied,
hatching was used in 70.6% of dichorionic compared to 89.5% of trichorionic IVF
triplets (p = 0.005); embryo transfer was performed on Day 5 or 6 compared to
Day 3 in 88.0% dichorionic vs 71.8% trichorionic (p = 0.028). Frozen sperm was
utilized more frequently with dichorionic than with trichorionic triplets,
26.0% vs 10.9% (p