TITLE:
Evolutionary Profile of Graves’ Disease in Children at Albert Royer National Children Hospital in Dakar
AUTHORS:
Babacar Niang, Lamine Thiam, Fatou Ly, Indou Dème Ly, Djibril Boiro, Amadou Sow, Aliou Thiongane, Aliou Abdoulaye Ndongo, Aminata Mbaye, Younoussa Keita, Abou Ba, Idrissa Demba Ba, Yaay Joor Dieng, Dienaba Fafa Cissé, Papa Matar Faye, Amadou Lamine Fall, Ousmane Ndiaye
KEYWORDS:
Graves’ Disease, Child, Antithyroid Drug, Remission, Senegal
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.9 No.2,
May
9,
2019
ABSTRACT: Graves’ disease is the most common cause of hyperthyroidism. Adequate
management is an area of controversy, especially when it comes to children. The
objective of our study was to assess the outcome of Graves’ disease treatment
in Albert Royer Children Hospital of Dakar. This was a retrospective study
conducted from 2001 to 2015, and which involved all children between 0 to 15
years of age who were being monitored in the Albert Royer National Children
Hospital. The evolutionary modalities were: stability, remission, failure,
relapse, lost to follow-up and death. The data were analyzed with SPSS software
version 20.0. For the comparisons, the KHI 2 or Fisher test was used
with a significance threshold (p e for 37
months were promising in 21 cases (30.43%), with 17 cases of remission (24.63%)
and 4 cases of stability (5.8%). Age older than 10, the initial ATD dose
greater than 1 mg/kg/day and the initial free T4 lower than 50 pmol/l were
significantly associated with remission with a p
value of 0.01; 0.024 and 0.004.