Werbrouck, J., De Ruyck, K., Duprez, F., Veldeman, L., Claes, K., et al. (2009) Acute Normal Tissue Reactions in Head and Neck Cancer Patients Treated with IMRT: Influence of Dose and Association with Genetic Polymorphisms in DNA DSB Repair Genes. International Journal of Radiation Oncology Biology Physics, 73, 1187-1195.
https://doi.org/10.1016/j.ijrobp.2008.08.073

has been cited by the following article:

• TITLE: Measuring Radiotherapy Setup Errors in IMRT Treated Head and Neck Cancer Patients Requiring Bilateral Neck Irradiation, NCI-Egypt Experience

  AUTHORS: May G. Ashour, Tarek H. Shouman, Ashraf H. Hassouna, Reem M. Emad El Din, Maha H. Mokhtar, Mohamed A. Khalil

  KEYWORDS: IMRT, CBCT, Setup Errors, Head and Neck

  JOURNAL NAME: Journal of Cancer Therapy, Vol.8 No.13, December 13, 2017

  ABSTRACT: Objective: We aim to quantify the magnitude of setup errors in intensity-modulated radiotherapy (IMRT) treated Head and Neck cancer patients and recommend appropriate PTV margin. Methods: 60 patients with head and neck cancer required bilateral neck irradiation were planned and treated by simultaneous integrated boost IMRT technique either treated radically or postoperative. Patients undergoing image-guided radiotherapy (IGRT) each with once weekly scheduled cone beam computed tomography (CBCT). The 3D displacements, systematic and random errors were calculated. The appropriate PTV expansion was determined using Van Herk’s formula. Results: Mean 3D displacement was 0.16 cm in the vertical direction, 0.14 cm in the horizontal direction and 0.16 cm in the longitudinal direction. Conclusion: Use of weekly CBCT allows the planning target volume (PTV) expansion to be reduced according to our setup. The appropriate clinical target volume (CTV)-PTV margin for our institute is 0.30 cm, 0.38 cm, and 0.33 cm in the horizontal, vertical, and longitudinal directions, respectively.