TITLE:
Analytical Procedures and Method Validation for Determination of Chlorimuron Ethyl in Sediments
AUTHORS:
Ramom Rachide Nunes, Bruno Henrique Froes Santos, Maria Olímpia de Oliveira Rezende
KEYWORDS:
Chlorimuron Ethyl, Sulphonylurea, Validation of Analytical Method, HPLC-UV
JOURNAL NAME:
Open Access Library Journal,
Vol.3 No.4,
April
21,
2016
ABSTRACT:
The present work describes the validation of an analytical method for
chromatographic determination of chlorimuron ethyl herbicide (compound of
sulphonylurea group) in sediments, in according with Brazilian legislation,
following the guidance and normative documents of INMETRO (DOQ-CGCRE-008) and
ANVISA (Resolution RE no. 899-2003). The results show that the chromatographic
method demonstrated to be selective, accurate, precision and linear over the
concentration range of 5.0 - 1000.0 μg·L﹣1. Besides, limits of quantitation and determination were
satisfactory, 29.48 and 8.84 μg·L﹣1, both determined by calibration curve. The method proposed
also showed good results for assays of recovery, with confidence intervals
between 80 and 100%, approximately, with accuracy and precision.