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has been cited by the following article:

• TITLE: Studying Molecular Aspects of the Blood-Brain Barrier Using an in Vitro Model: Contribution of a Global Proteomics Strategy

  AUTHORS: Yannis Karamanos

  KEYWORDS: Blood-Brain Barrier; BBB; Endothelial Cells; Proteomics

  JOURNAL NAME: Journal of Biosciences and Medicines, Vol.2 No.1, March 6, 2014

  ABSTRACT: A global proteomics strategy was initiated to decipher molecular mechanisms associated with the blood-brain barrier (BBB) phenotype of the brain capillary endothelial cells. The different methods implemented were shown complementarily. The main results obtained using an in vitro BBB model allowed highlighting the role of several protein actors of cytoskeleton remodelling, the involvement of the asymmetric dimethylarginine pathway in regulating endothelial function and the role of tissue non-specific alkaline phosphatase in the regulation of endothelial permeability.