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Author(s): |
Bin-wei Wu, Zhejiang Sci-Tech University1. The Key Laboratory of Advanced Textile Materials and Manufacturing Technology of Ministry of Education , Hangzhou, 310018,China;2. Zhejiang Sci-Tech University, College of Materials and Textiles ,Hangzhou ,310018,China；
Shi-zhuang Xue, Zhejiang Sci-Tech University1. The Key Laboratory of Advanced Textile Materials and Manufacturing Technology of Ministry of Education , Hangzhou, 310018,China;2. Zhejiang Sci-Tech University, College of Materials and Textiles ,Hangzhou ,310018,China；
Hai-lin Zhu, Zhejiang Sci-Tech University, College of Science, Hangzhou, 310018, China
Xin-xing Feng, Zhejiang Sci-Tech University1. The Key Laboratory of Advanced Textile Materials and Manufacturing Technology of Ministry of Education , Hangzhou, 310018,China;2. Zhejiang Sci-Tech University, College of Materials and Textiles ,Hangzhou ,310018,China；
Jian-yong Chen, Zhejiang Sci-Tech University1. The Key Laboratory of Advanced Textile Materials and Manufacturing Technology of Ministry of Education , Hangzhou, 310018,China;2. Zhejiang Sci-Tech University, College of Materials and Textiles ,Hangzhou ,310018,China； |
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Abstract: |
To develop a small-diameter tissue engineering blood vessel, the silk fibroin (SF)/poly (butylene succinate) (PBS) tubular scaffolds were fabricated via electrospinning. In the electrospinning process, the electrospun SF/PBS composite tubular scaffolds were collected on a 3D collector instead of traditional 2D collector. The effects of 3D collector and process parameters of electrospinning on the morphologies of the tubular scaffolds were investigated. FTIR was used to study the secondary structure of SF. The mechanical properties and the porosities of the tubular fiber materials were characterized. The results showed that SF/PBS composite tubular materials with different sizes and shapes could be prepared by changing the voltage, TCD and the structure of 3D collectors. The porosity, the tensile stress, the elongation at break and the burst pressure of the composite tubular scaffold were 84.6%, 4.31 MPa, 46.21% and 358 kPa, respectively.
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