Article citationsMore>>
Invernizzi, P., Miozzo, M., Selmi, C., Persani, L., Battezzati, P.M., Zuin, M., Lucchi, S., Meroni, P.L., Marasini, B., Zeni, S., Watnik, M., Grati, F.R., Simoni, G., Gershwin, M.E. and Podda, M. (2005) X Chromosome Monosomy: A Common Mechanism for Autoimmune Diseases. Journal of Immunology, 175, 575-578.
http://dx.doi.org/10.4049/jimmunol.175.1.575
has been cited by the following article:
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TITLE:
Epidemiological, Pathophysiological and Clinical Peculiarities of Graves’ Disease in Children with Down and Turner Syndrome: A Literature Review
AUTHORS:
Malgorzata Wasniewska, Tommaso Aversa, Filippo De Luca, Mariella Valenzise, Maria Francesca Messina, Fortunato Lombardo
KEYWORDS:
Autoimmune Thyroid Diseases, Chromosomopathies, Clinical Course, Hyperthyroidism, Prevalence
JOURNAL NAME:
Health,
Vol.6 No.12,
June
23,
2014
ABSTRACT: Aim: to describe the salient relationships between Graves’ disease (GD) and both Turner syndrome (TS) and Down syndrome (DS). Design: to conduct a secondary analysis of current literature on this topic. Results: 1) the prevalences of GD in TS and in DS young patients are 1.7% and 6.5‰, respectively, i.e. higher than that in pediatric general population (around 1‰); 2) in both these chromosomopathies GD presentation is often preceded by Hashimoto’s thyroiditis (HT) antecedents; 3) in both TS and DS, GD presents with a clinical picture very similar to that observed in GD patients without these chromosomopathies; 4) in TS, clinical course of GD under pharmacological therapy is very similar to that observed in non-TS girls; 5) in DS, clinical course of GD under pharmacological therapy is less severe than that in non-DS patients. Conclusions: in the children with either TS or DS, GD is characterized by two common epidemiological peculiarities, i.e. increased prevalence rate and elevated frequency of HT antecedents.
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