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has been cited by the following article:

• TITLE: Development and Validation of New RP-HPLC Method for the Estimation of Alfuzosin Hydrochloride in Bulk and Tablet Dosage Form

  AUTHORS: Vandana P. Patil, Subhash J. Devdhe, Suwarna H. Kale, Vijay J. Nagmoti, Sadanand D. Kurhade, Yuvraj R. Girbane, Mahesh T. Gaikwad

  KEYWORDS: Alfuzosin HCl; RP-HPLC; Linearity; Precision; Accuracy; Robustness; Ruggedness

  JOURNAL NAME: American Journal of Analytical Chemistry, Vol.4 No.1, January 18, 2013

  ABSTRACT: A reverse phase high performance liquid chromatographic method (HPLC) has been developed for the estimation of Alfuzosin hydrochloride (ALH) in the pharmaceutical formulation using RP-C18 column. The mobile phase (Tetrahydrofuran, Acetonitrile and buffer (pH 3.50) was pumped at a flow rate of 1.5 ml/min in the ratio of 1:20:80 and the eluents were monitored at 254.0 nm. Linearity was obtained in the concentration range of 80 - 120 μg/mL for ALH. The method was statistically validated and RSD was found to be less than 2% indicating high degree of accuracy and precision of the proposed HPLC method. Due to its simplicity, rapidness, high precision and accuracy, the proposed HPLC method may be used for determination of Alfuzosin hydrochloride in bulk drugs and in pharmaceutical dosage form.