TITLE:
Impact of Factors Associated with Chronic Complications in the Life of Sickle Cell Patients in Kinshasa
AUTHORS:
Janine Mpesi Kimboko, Steve Dibere Kodondi, Freddy Nsiamakani Tukebana, Nancy Dora Ndaya, Julien Alendi Ntaongo, Doudou Boloweti Batumbo, Lucrèce M. Délicat-Lomboet, Harry Cesar Ntumba Kayembe, Fridolin Kule-Koto Kodondi
KEYWORDS:
Sickle Cell Disease, Chronic Complications, Associated Factors
JOURNAL NAME:
Open Access Library Journal,
Vol.11 No.2,
February
28,
2024
ABSTRACT: Context: Studies describing the factors associated with chronic complications and their impact on the life of adult sickle cell patients are rare. Objective: Contribute to improving the care of sickle cell patients in Kinshasa through the analysis of the impact of factors associated with chronic complications of sickle cell disease. Method: This is a cross sectional analytical study. Results: This research was carried out in a cross-sectional manner on 230 sickle cell pa-tients aged at least 15 years recruited at the Center for Mixed Medicine and SS anemia and also in three associations of sickle cell disease patients in Kinsha-sa. The median age was 23.55 years (extremes 1543 years), the majority of whom were female (58.3%), with a sex ratio M/F = 0.72. Chronic complica-tions were mainly infectious (47.2%), followed by hemolytic (27.6%) and is-chemic (25.2%). Occupation, level of education, socioeconomic level (social class), and the presence and number of sickle cell siblings in the family were identified as potential factors for the occurrence of chronic complications. Conclusion: Sickle cell patients in Kinshasa have a low overall Quality of Life, particularly in its physical component, which is significantly affected by psy-chological limitations. Thus, improving the living conditions of sickle cell pa-tients, better follow-up and accessibility to care should contribute to improving the quality of Life of sickle cell patients in DRC.