TITLE:
Current Research Status of MicroRNAs in Squamous Cell Carcinoma of the Tongue
AUTHORS:
Wenjing Wang, Yi Liu
KEYWORDS:
MicroRNAs, Tongue Squamous Cell Carcinoma Cells, Tumor, Pathogenesis
JOURNAL NAME:
Open Journal of Stomatology,
Vol.14 No.2,
February
9,
2024
ABSTRACT: Tongue squamous cell carcinoma (TSCC) is the most invasive type of oral malignant tumor, posing a serious threat to human life and health. Its pathogenesis is complex and has a high degree of malignancy. Recurrence and metastasis often lead to poor prognosis. MicroRNAs are a type of single stranded small molecule RNA with only 18 - 25 nucleotides, which can regulate the expression of various genes and participate in the occurrence and development of tumors. Studies have found that microRNA expression profiling can serve as a reliable and stable biological indicator for early diagnosis and prognosis of tumors. This article provides a review of the research status of MicroRNAs in squamous cell carcinoma of the tongue.