TITLE:
Helicobacter Pylori Infection in Brazzaville: Comparative Study of Two Identification Tests
AUTHORS:
Ngala Akoa Itoua-Ngaporo, Lucie C. A. I. O. Ikobo, Arnaud Mongo-Onkouo, Jile Florent Mimiesse Monamou, Clausina Philestine Ahoui Apendi, Rody Stéphane Ngami, Marlyse Ngalessami Mouakosso, Deby Gassaye, Blaise Irenée Atipo Ibara, Jean-Rosaire Ibara
KEYWORDS:
Helicobacter Pylori, Identification Tests, Brazzaville
JOURNAL NAME:
Open Journal of Gastroenterology,
Vol.9 No.11,
November
26,
2019
ABSTRACT: Objective: To determine the place of two identification tests
for Helicobacter pylori infection available in Congo. Materials and Methods: This was a comparative study carried out in two digestive endoscopy centers in
Brazzaville from 1 January to 31 May 2018. Symptomatic patients referred for
upper gastrointestinal endoscopy were included systematically. The frequency of
infection was determined from two identification tests, namely the rapid urease
test in gastric biopsies and the detection of antigen (Ag) for the germ in the
stool. The criterion for judging the presence of the germ in each patient was
the positivity of at least one of the two tests. The McNEMAR X2 test (p Results: During the study period,
137 consenting patients were included, including 62 men and 75 women. The
overall incidence of Helicobacter pylori (Hp) infection was 79.6% (109/28). Of
the 137 patients, 18 were urease positive only; 6 were
looking for Hp Ag in the stool, and 85 were in the two tests. The frequency of
infection was 75.2% (103/137) with the rapid urease test and 66.4% (91/137)
with the Hp Ag test in stool. The rapid urease test proved more reliable in the
diagnosis of Helicobacter pylori infection than the stool antigen test.