TITLE:
Antioxidant Activity of the Natural Flavonoid 7-Hydroxy-5,6,4’-trimethoxyflavone Isolated from the Leaves of Lippia rugosa A. Chev
AUTHORS:
Jean Momeni, Jean Paul Tsopmejio, Francine T. Nkouam, Martin B. Ngassoum
KEYWORDS:
7-Hydroxy-5, 6, 4’-trimethoxyflavone, Phenolic Compounds, Antioxidant Activity, DPPH Assay, Lippia rugosa, Organic Extracts
JOURNAL NAME:
Natural Science,
Vol.8 No.2,
February
22,
2016
ABSTRACT: Phytochemical
studies and antioxidant activities were carried out on n-hexane, ethyl acetate,
ethanol and methanol extracts of the leaves of Lippia rugosa A. Chev (Verbenaceae),
a medicinal plant used traditionally in the Cameroonian savannah’s region to protect
foodstuffs and to cure degenerative diseases. Results indicated that theses extracts
contain terpenoids, phenolic and flavonoid compounds. Except the n-hexane extract,
all of the obtained extracts exhibit antioxidant activities with the ethanol extract being the most effective with an inhibition
percentage of 85.668% ± 1.233% and an inhibition concentration (IC50)
of 58 μg/ml (R2 = 0.987, P 50) of
221 μg/ml (R2 = 0.966, P L. rugosa and its antioxidant activity evaluated.