Poulain, D., Faille, C., Delaunoy, C., Jacquinot, P.M., Trinel, P.A. and Camus, D. (1993) Probable Presence of β(1-2)-Linked Oligomannosides that Act as Human Immunoglobulin G3 Epitopes and Are Distributed over a Candida albicans 14- to 18-Kilodalton Antigen. Infection and Immunity, 61, 1164-1166.

has been cited by the following article:

• TITLE: Determination of α-1,3-Linked Mannose Residue in the Cell Wall Mannan of Candida tropicalis NBRC 1400 Strain

  AUTHORS: Takuya Kuraoka, Takayoshi Yamada, Akito Ishiyama, Hiroko Oyamada, Yukiko Ogawa, Hidemitsu Kobayashi

  KEYWORDS: Candida tropicalis, Pathogenic Yeast, Cell Wall Mannan, Antigenic Oligomannosyl Side Chain, Acetolysis, α-1, 3-Linked Mannose Residue

  JOURNAL NAME: Advances in Microbiology, Vol.10 No.1, January 3, 2020

  ABSTRACT: To investigate the chemical structure of cell wall mannan obtained from pathogenic yeast, Candida tropicalis NBRC 1400 (former antigenic standard strain, IFO 1400). As a result of two-dimensional NMR analysis, it was shown that the mannan of this strain is composed of α-1,6-, α-1,3-, α-1,2- and β-1,2-linked mannose residues. In this research, the mannan was subjected to three degradation procedures, acid-treatment, α-mannosidase, and acetolysis under two conditions in order to determine the chemical structure of the antigenic oligomannosyl side chains in this molecule. The 1H-nuclear magnetic resonance spectra of resultant oligosaccharides, pentaose and hexaose, demonstrated the existence of the oligomannosyl side chains corresponding to Manα1-3Manα1-2Manα1-2Manα1-2Man and Manα1-3Manα1-2Manα1-2Manα1-2Manα1-2Man, respectively, which have previously also been found in Candida albicans serotype A strain mannans. These findings indicate that C. tropicalis and C. albicans serotype A have no significant difference in the chemical structure of these cell wall mannans. Therefore, it can be interpreted that it is extremely difficult to distinguish both species by targeting the antigenic group in these mannans.